X inactivation:: Tsix and Xist as yin and yang

被引：27

作者：

Mlynarczyk, SK ^{[1
]}

Panning, B ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Biochem & Biophys, San Francisco, CA 94143 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 24期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0960-9822(00)00847-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new study shows that expression of Tsix, an antisense Xist gene, can be controlled by imprinting, and that high Tsix activity during X inactivation can protect the future active X chromosome from silencing by Xist. Tsix and Xist seem to have a yin and yang relationship, with opposite effects on X inactivation.

引用

页码：R899 / R903

页数：5

共 16 条

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