Evaluation of a spinning disc reactor for continuous processing

被引:43
作者
Brechtelsbauer, C [1 ]
Lewis, N [1 ]
Oxley, P [1 ]
Ricard, F [1 ]
Ramshaw, C [1 ]
机构
[1] SmithKline Beecham Pharmaceut, Leigh TN11 9AN, Kent, England
关键词
D O I
10.1021/op0000834
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
As part of an evaluation of equipment aimed at process intensification, use of a continuously operating spinning disc reactor (SDR) was investigated. Results obtained for two organic reactions and one crystallisation are discussed. The SDR was found to be a useful tool for revealling intrinsically fast kinetics as well as for optimising a process with such kinetics. Control of particle size distribution was demonstrated with the crystallisation investigated.
引用
收藏
页码:65 / 68
页数:4
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