Single potassium ion seeks open channel for transmembrane travels: tales from the KcsA structure

被引：3

作者：

Gouaux, E ^{[1
]}

机构：

[1] Columbia Univ, Dept Biochem & Mol Biophys, New York, NY 10032 USA

来源：

STRUCTURE WITH FOLDING & DESIGN | 1998年 / 6卷 / 10期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

D O I：

10.1016/S0969-2126(98)00122-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Potassium channels selectively catalyze potassium transport across cell membranes. Over the past five decades, a multitude of potassium channel models have been proposed. The recent crystal structure determination of the KcsA potassium channel confirms, corrects and expands our understanding of a fundamental biological catalyst, revealing the basis of exquisite selectivity and near diffusion-limited throughput.

引用

页码：1221 / 1226

页数：6

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