Streptococcus pneumoniae respiratory tract infections

被引：36

作者：

Klugman, KP

Feldman, C

机构：

[1] Emory Univ, Rollins Sch Publ Hlth, Dept Int Hlth, Atlanta, GA 30322 USA

[2] S African Inst Med Res, Sch Pathol, MRC, Wits Pneumococcal Dis Res Unit, Johannesburg, South Africa

[3] Univ Witwatersrand, ZA-2050 Johannesburg, South Africa

[4] Johannesburg Hosp, Dept Med, Div Pulmonol, Johannesburg, South Africa

[5] Univ Witwatersrand, Johannesburg, South Africa

来源：

CURRENT OPINION IN INFECTIOUS DISEASES | 2001年 / 14卷 / 02期

关键词：

D O I：

10.1097/00001432-200104000-00011

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

This review describes recent contributions to our understanding of pneumococcal pneumonia, Two genes have been described that encode enzymes involved with the biosynthesis of muropeptides, These enzymes may be novel antibiotic targets. The clinical impact of increasing antibiotic resistance on the treatment of pneumonia is the particular focus of the review. As resistant strains are more commonly associated with severe infections in patients with underlying disease, the interpretation of an association of resistance with poor clinical outcome is complicated. Curr Opin Infect Dis 14:173-179. (C) 2001 Lippincott Williams & Wilkins.

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页码：173 / 179

页数：7

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