Treatment of Gastric Cancer With Peritoneal Carcinomatosis by Cytoreductive Surgery and HIPEC: A Systematic Review of Survival, Mortality, and Morbidity

被引:199
作者
Gill, Richdeep S. [1 ]
Al-Adra, David P. [1 ]
Nagendran, Jeevan [1 ]
Campbell, Sandy [2 ]
Shi, Xinzhe [3 ]
Haase, Erika [1 ]
Schiller, Daniel [1 ]
机构
[1] Univ Alberta, Dept Surg, Edmonton, AB, Canada
[2] Univ Alberta, Lib Serv, Edmonton, AB, Canada
[3] Royal Alexandra Hosp, Ctr Adv Minimally Invas Surg CAMIS, Edmonton, AB, Canada
关键词
peritoneal carcinomatosis; gastric cancer; HIPEC; cytoreductive surgery; HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY; COLORECTAL-CANCER; RANDOMIZED-TRIAL; LEARNING-CURVE; DOXORUBICIN; MALIGNANCY; CISPLATIN; THERAPY; CHEMOHYPERTHERMIA; PHARMACOKINETICS;
D O I
10.1002/jso.22017
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Gastric cancer with peritoneal carcinomatosis has an extremely poor prognosis, which may be improved with cytoreductive surgery (CRS) combined with heated intraperitoneal chemotherapy (HIPEC). We systematically reviewed the literature regarding the efficacy of CRS + HIPEC in these patients. Electronic databases were searched from 2000 to 2010. Following CRS + HIPEC, overall median survival was 7.9 months and improved to 15 months for patients with completeness of cytoreduction scores of 0/1, however with a 30-day mortality rate of 4.8%. J. Surg. Oncol. 2011;104:692-698. (C) 2011 Wiley Periodicals, Inc.
引用
收藏
页码:692 / 698
页数:7
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