[1] Univ Toronto, Heart & Stroke Richard Lewar Ctr, Toronto, ON, Canada
[2] Univ Toronto, Peter Munk Cardiac Ctr, Toronto, ON, Canada
[3] Univ Toronto, Div Nephrol, Sunnybrook Hlth Sci Ctr, Toronto, ON, Canada
[4] Univ Calgary, Libin Cardiovasc Inst Alberta, Calgary, AB, Canada
[5] Univ Calgary, Cardiac Wellness Inst Calgary, Calgary, AB, Canada
[6] McMaster Univ, Dept Oncol, Hamilton, ON, Canada
[7] McMaster Univ, Dept Clin Epidemiol & Biostat, Hamilton, ON, Canada
[8] Univ Toronto, Dept Family & Community Med, Li Ka Shing Knowledge Inst, St Michaels Hosp, Toronto, ON M5S 1A1, Canada
[9] Canadian Inst Hlth Res, Inst Circulatory & Resp Hlth, Ottawa, ON, Canada
[10] Univ British Columbia, Dept Family Med, Vancouver, BC V5Z 1M9, Canada
[11] McGill Univ, Dept Med, Montreal, PQ, Canada
[12] McGill Univ, Dept Clin Epidemiol, Montreal, PQ, Canada
[13] Dalhousie Univ, Dept Med, Halifax, NS, Canada
[14] Univ Calgary, Dept Med, Calgary, AB, Canada
[15] Univ Calgary, Dept Biochem & Mol Biol, Calgary, AB, Canada
[16] Univ Ottawa, Minto Prevent & Rehabil Ctr, Inst Heart, Ottawa, ON, Canada
[17] Univ Toronto, Ctr Addict & Mental Hlth, Toronto, ON, Canada
[18] Childrens Hosp, Eastern Ontario Res Inst, Ottawa, ON, Canada
[19] Univ British Columbia, Cardiovasc Physiol & Rehabil Lab, Expt Med Program, Vancouver, BC V5Z 1M9, Canada
[20] Univ Calgary, Dept Family Med, Calgary, AB, Canada
[21] Univ Manitoba, Endocrinol Sect, Hlth Sci Ctr, Winnipeg, MB, Canada
[22] Univ Toronto, St Michaels Hosp, Keenan Res Ctr, Li Ka Shing Knowledge Inst, Toronto, ON M5B 1W8, Canada