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WT1 - more than a transcription factor?

被引：53
作者：
Englert, C [1 ]
机构：
[1] Forschungszentrum Karlsruhe, Inst Genet, D-76021 Karlsruhe, Germany
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 10期
关键词：
D O I：
10.1016/S0968-0004(98)01277-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Wilms tumor-suppressor gene WT1 was originally identified through its involvement in the development of a pediatric kidney tumor. Recent genetic data show that mutations in the WT1 gene cause a variety of other diseases, and new biochemical evidence suggests that the WT1 protein is not only a transcription factor but might also act at the post-transcriptional level.
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页码：389 / 393
页数：5
相关论文
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