Sodwanone S, a triterpene from the marine sponge Axinella weltneri

被引：21

作者：

Bon, CFL

Berrué, F

Thomas, OP

Reyes, F

Amade, P ^{[1
]}

机构：

[1] UNSA, Fac Sci, Chim Bioorgan Lab, CNRS UMR 6001,Parc Valrose, F-06108 Nice, France

[2] PharmaMar SA, Dept Med Chem, Madrid 28770, Spain

来源：

JOURNAL OF NATURAL PRODUCTS | 2005年 / 68卷 / 08期

关键词：

D O I：

10.1021/np050100o

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The bioassay-guided fractionation of the crude extract of the marine sponge Axinella weltneri led to the isolation and the identification of a new triterpene named sodwanone S (1), with an uncommon oxepane-cyclohexane system, along with the known sodwanones A and G. The structure was elucidated using spectroscopic data, and the biological activity was evaluated against 13 human tumor cell lines. A biogenetic pathway of this new compound is also proposed.

引用

页码：1284 / 1287

页数：4

共 19 条

[1] Yardenone A and B:: New cytotoxic triterpenes from the Indian Ocean sponge Axinella cf bidderi
Carletti, I
Long, C
Funel, C
Amade, P
[J]. JOURNAL OF NATURAL PRODUCTS, 2003, 66 (01): : 25 - 29
[2] SIPHONELLINOL, A NEW TRITERPENE FROM THE MARINE SPONGE SIPHONOCHALINA-SIPHONELLA
CARMELY, S
LOYA, Y
KASHMAN, Y
[J]. TETRAHEDRON LETTERS, 1983, 24 (34) : 3673 - 3676
[3] THE SIPHOLANES - A NOVEL GROUP OF TRITERPENES FROM THE MARINE SPONGE SIPHONOCHALINA-SIPHONELLA
CARMELY, S
KASHMAN, Y
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (20) : 3517 - 3525
[4] New additional triterpenoids from the Mediterranean sponge Raspaciona aculeata
Ciavatta, ML
Scognamiglio, G
Trivellone, E
Bisogno, T
Cimino, G
[J]. TETRAHEDRON, 2002, 58 (24) : 4943 - 4948
[5] A NEW TRITERPENOID SKELETON FROM THE MEDITERRANEAN SPONGE RASPACIONA-ACULEATA - STRUCTURE OF RASPACIONIN
CIMINO, G
CRISPINO, A
MATTIA, CA
MAZZARELLA, L
PULITI, R
TRIVELLONE, E
URIZ, MJ
[J]. TETRAHEDRON LETTERS, 1990, 31 (45) : 6565 - 6568
[6] RASPACIONIN-A - A NOVEL REARRANGED TRITERPENOID FROM THE MEDITERRANEAN SPONGE RASPACIONA-ACULEATA
CIMINO, G
CRISPINO, A
EPIFANIO, RD
MADAIO, A
MATTIA, CA
MAZZARELLA, L
PULITI, R
TRIVELLONE, E
URIZ, M
[J]. TETRAHEDRON, 1992, 48 (41) : 9013 - 9022
[7] MINOR TRITERPENOIDS FROM THE MEDITERRANEAN SPONGE, RASPACIONA-ACULEATA
CIMINO, G
MADAIO, A
TRIVELLONE, E
URIZ, M
[J]. JOURNAL OF NATURAL PRODUCTS, 1994, 57 (06): : 784 - 790
[8] RASPACIONIN-B, A FURTHER TRITERPENOID FROM THE MEDITERRANEAN SPONGE RASPACIONA-ACULEATA
CIMINO, G
CRISPINO, A
MADAIO, A
TRIVELLONE, E
URIZ, M
[J]. JOURNAL OF NATURAL PRODUCTS, 1993, 56 (04): : 534 - 538
[9] Marine polyether triterpenes
Fernández, JJ
Souto, ML
Norte, M
[J]. NATURAL PRODUCT REPORTS, 2000, 17 (03) : 235 - 246
[10] New cytotoxic steroids from the Indian ocean sponge Axinella cf. bidderi
Funel, C
Berrué, F
Roussakis, C
Rodriguez, RF
Amade, P
[J]. JOURNAL OF NATURAL PRODUCTS, 2004, 67 (03): : 491 - 494

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