Synthesis of carbohydrate-conjugated nanoparticles and quantum dots

被引:82
作者
Earhart, Christopher [1 ]
Jana, Nikhil R. [1 ]
Erathodiyil, Nandanan [1 ]
Ying, Jackie Y. [1 ]
机构
[1] Inst Bioengn & Nanotechnol, Singapore 138669, Singapore
关键词
D O I
10.1021/la800066g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nanoparticle-based probes are emerging as alternatives to molecular probes due to their various advantages, such as bright and tunable optical property, enhanced chemical and photochemical stability, and ease of introduction of multifunctionality. This work presents a simple and general approach for functionalizing various nanoparticle systems for use as glycobiological probes. Silica-coated nanoparticles of Ag, Fe3O4, and ZnS-CdSe were synthesized and functionalized with dextran. The resulting 10-40-nm-sized particles were robust, water-soluble, colloidally stable, and biochemically active.
引用
收藏
页码:6215 / 6219
页数:5
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