Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex

被引：8

作者：

Kus, L ^{[1
]}

Mazzone, SB

Paxinos, G

Geraghty, DP

机构：

[1] Univ New S Wales, Sch Psychol, Sydney, NSW 2052, Australia

[2] Univ Tasmania, Dept Biomed Sci, Launceston, Tas 7250, Australia

来源：

BRAIN RESEARCH | 1998年 / 794卷 / 02期

基金：

英国医学研究理事会;

关键词：

substance P; neurokinin; 1; receptor; autoradiography; human visual cortex;

D O I：

10.1016/S0006-8993(98)00270-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This study utilised autoradiography to examine [I-125]-Bolton Hunter substance P (BHSP) binding in postmortem human visual cortex. In the primary visual area, layers I-III, IVC and VI exhibited low levels of BHSP binding, while high levels were observed in layers IVB and V. Because cells in layers IVB and V are known to be involved in processing direction-specific stimuli, it is possible that SP plays a role in modulating this visual process. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：309 / 312

页数：4

共 22 条

[1] TACHYKININS PREFERENTIALLY EXCITE CERTAIN COMPLEX CELLS IN THE INFRAGRANULAR LAYERS OF FELINE STRIATE CORTEX [J].

ALBUS, K ;

CHAO, HHA ;

HICKS, TP .

BRAIN RESEARCH, 1992, 587 (02) :353-357

[2] NK1 RECEPTOR EXPRESSION BY CHOLINERGIC INTERNEURONS IN HUMAN STRIATUM [J].

AUBRY, JM ;

LUNDSTROM, K ;

KAWASHIMA, E ;

AYALA, G ;

SCHULZ, P ;

BARTANUSZ, V ;

KISS, JZ .

NEUROREPORT, 1994, 5 (13) :1597-1600

[3] QUANTITATIVE AUTORADIOGRAPHIC ANALYSIS OF THE DISTRIBUTION OF BINDING-SITES FOR [I-125] BOLTON HUNTER DERIVATIVES OF ELEDOISIN AND SUBSTANCE-P IN THE RAT-BRAIN [J].

BEAUJOUAN, JC ;

TORRENS, Y ;

SAFFROY, M ;

GLOWINSKI, J .

NEUROSCIENCE, 1986, 18 (04) :857-875

[4] ACTIVITY-DEPENDENT CHANGES IN GAD AND PREPROTACHYKININ MESSENGER-RNAS IN VISUAL-CORTEX OF ADULT MONKEYS [J].

BENSON, DL ;

HUNTSMAN, MM ;

JONES, EG .

CEREBRAL CORTEX, 1994, 4 (01) :40-51

[5] THE REGIONAL DISTRIBUTION OF SOMATOSTATIN, SUBSTANCE-P AND NEUROTENSIN IN HUMAN-BRAIN [J].

COOPER, PE ;

FERNSTROM, MH ;

RORSTAD, OP ;

LEEMAN, SE ;

MARTIN, JB .

BRAIN RESEARCH, 1981, 218 (1-2) :219-232

[6] PHYLOGENY OF TACHYKININ RECEPTOR LOCALIZATION IN THE VERTEBRATE CENTRAL-NERVOUS-SYSTEM - APPARENT ABSENCE OF NEUROKININ-2 AND NEUROKININ-3 BINDING-SITES IN THE HUMAN BRAIN [J].

DIETL, MM ;

PALACIOS, JM .

BRAIN RESEARCH, 1991, 539 (02) :211-222

[7] Neurons in the rat occipital cortex co-expressing the substance P-receptor and GABA: A comparison between in vivo and organotypic cultures [J].

Echevarria, D ;

Matute, C ;

Albus, K .

EUROPEAN JOURNAL OF NEUROSCIENCE, 1997, 9 (07) :1530-1535

[8]

HENDRY SHC, 1988, J NEUROSCI, V8, P1225

[9] Dual role of substance P GABA axons in cortical neurotransmission: Synaptic triads on pyramidal cell spines and basket-like innervation of layer II-III calbindin interneurons in primate prefrontal cortex [J].

Jakab, RL ;

GoldmanRakic, P ;

Leranth, C .

CEREBRAL CORTEX, 1997, 7 (04) :359-373

[10] DISTRIBUTION OF EXCITATORY AND INHIBITORY AMINO-ACID, SIGMA, MONOAMINE, CATECHOLAMINE, ACETYLCHOLINE, OPIOID, NEUROTENSIN, SUBSTANCE-P, ADENOSINE AND NEUROPEPTIDE-Y RECEPTORS IN HUMAN MOTOR AND SOMATOSENSORY CORTEX [J].

JANSEN, KLR ;

FAULL, RLM ;

DRAGUNOW, M ;

LESLIE, RA .

BRAIN RESEARCH, 1991, 566 (1-2) :225-238

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