Steroid hormones and their receptors in the brain

被引：34

作者：

Kawata, M ^{[1
]}

Yuri, K ^{[1
]}

Ozawa, H ^{[1
]}

Nishi, M ^{[1
]}

Ito, T ^{[1
]}

Hu, ZT ^{[1
]}

Lu, HP ^{[1
]}

Yoshida, M ^{[1
]}

机构：

[1] Kyoto Prefectural Univ Med, Dept Neurobiol & Anat, Kamigyo Ku, Kyoto 602, Japan

来源：

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY | 1998年 / 65卷 / 1-6期

关键词：

D O I：

10.1016/S0960-0760(98)00026-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Steroid hormones regulate several important functions of the brain by altering the expression of particular genes through their receptors. First in this paper the localization of glucocorticoid receptor immunoreactivity and mRNA in the brain was examined. Second biphasic effects of glucocorticold on the hippocampus was described and particular emphasis was given on the apoptosis. Third the significance of estrogen receptor in the sexually dimorphic areas was discussed. These results suggest that steroids modulate the gene expression along with the alteration of cell structures in a different manner in a tissue-specific pattern. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：273 / 280

页数：8

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