Comparison of the outcome and treatment of psychosis in people of Caribbean origin living in the UK and British Whites - Report from the UK700 trial

Background The comparative outcome of psychosis in British Whites and UK African-Caribbeans is unclear. Some report that African - Caribbeans have worse outcome, whereas others claim better symptomatic outcome and a more benign course. Aims To a compare the course, outcome and treatment of psychosis in African Caribbeans and British Whites in a large multi-centre sample. Method A secondary analysis of 708 patients with research diagnostic criteria defined psychosis from a 2-year, randomised controlled trial of case management. Outcome measures (hospitalisation, illness course, self-harm. social disability and treatment received) were adjusted for socio-economic and clinical differences between groups at baseline using regression analysis. Results African-Caribbeans were less likely to have a continuous illness and to receive treatment with antidepressants or psychotherapy. Conclusions The outcome of psychosis is complex but differs between UK African-Caribbeans and British Whites. This may reflect risk factors that increase the rate of psychosis in UK African Caribbeans. Treatment differences require further investigation.