Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009)

被引：10

作者：

Boffetta, Paolo ^{[1
,2
]}

Colditz, Graham A. ^{[3
]}

Potter, John D. ^{[4
]}

Kolonel, Laurence ^{[5
]}

Robson, Paula J. ^{[6
]}

Malekzadeh, Reza ^{[7
]}

Seminara, Daniela ^{[8
]}

Goode, Ellen L. ^{[9
]}

Yoo, Keun-Young ^{[10
]}

Demers, Paul ^{[11
]}

Gallagher, Richard ^{[12
]}

Prentice, Ross ^{[4
]}

Yasui, Yutaka ^{[13
]}

O'Doherty, Kieran ^{[14
]}

Petersen, Gloria M. ^{[9
]}

Ulrich, Cornelia M. ^{[4
,15
,16
]}

Csizmadi, Ilona ^{[17
]}

Amankwah, Ernest K. ^{[17
]}

Brockton, Nigel T. ^{[17
]}

Kopciuk, Karen ^{[17
]}

McGregor, S. Elizabeth ^{[17
]}

Kelemen, Linda E. ^{[17
]}

机构：

[1] Mt Sinai Sch Med, Tisch Canc Inst, New York, NY 10029 USA

[2] Int Prevent Res Inst, F-69006 Lyon, France

[3] Washington Univ, Inst Publ Hlth, St Louis, MO 63110 USA

[4] Fred Hutchinson Canc Res Ctr, Div Publ Hlth Sci, Seattle, WA 98109 USA

[5] Univ Hawaii, Canc Res Ctr, Honolulu, HI 96813 USA

[6] Alberta Hlth Serv Canc Care, Dept Populat Hlth Res, Edmonton, AB T5N 3T2, Canada

[7] Univ Tehran Med Sci, Shariati Hosp, Digest Dis Res Ctr, Tehran 14117, Iran

[8] NCI, Bethesda, MD 20892 USA

[9] Mayo Clin, Coll Med, Dept Hlth Sci Res, Rochester, MN 55905 USA

[10] Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul 110799, South Korea

[11] Univ British Columbia, Sch Environm Hlth, Vancouver, BC V6T 1Z2, Canada

[12] BC Canc Agcy, Canc Control Res Program, Vancouver, BC, Canada

[13] Univ Alberta, Sch Publ Hlth, Edmonton, AB T5R 3B9, Canada

[14] Univ British Columbia, W Maurice Young Ctr Appl Eth, Vancouver, BC V6T 1Z2, Canada

[15] German Canc Res Ctr, D-69120 Heidelberg, Germany

[16] Natl Ctr Tumor Dis NCT, D-69120 Heidelberg, Germany

[17] Alberta Hlth Serv Canc Care, Dept Populat Hlth Res, Calgary, AB T2N 4N2, Canada

来源：

CANCER CAUSES & CONTROL | 2011年 / 22卷 / 03期

基金：

加拿大健康研究院;

关键词：

Biobanks; Cohort studies; Consortia; Cancer; Ethics; Data harmonization; Molecular epidemiology; CHILDHOOD-CANCER SURVIVOR; BREAST-CANCER; RESOURCE; BIOBANKS; DESIGN; HEALTH; INDIA;

D O I：

10.1007/s10552-010-9717-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report.

引用

页码：463 / 468

页数：6

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