Ligands for palladium-catalyzed cross-couplings of alkyl halides: Use of an alkyldiaminophosphane expands the scope of the Stille reaction

被引：78

作者：

Tang, HF ^{[1
]}

Menzel, K ^{[1
]}

Fu, GC ^{[1
]}

机构：

[1] MIT, Dept Chem, Cambridge, MA 02139 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 41期

关键词：

cross-coupling; homogeneous catalysis; palladium; phosphane ligands; Stille reaction;

D O I：

10.1002/anie.200352668

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Alkyldiaminophosphanes (PR(NR′2)2) are a new class of ligands for palladium-catalyzed cross-couplings of alkyl halides (see scheme). In comparison with trialkylphosphanes, alkyldiaminophosphanes furnish more versatile catalysts for Stille reactions of alkyl bromides and achieve efficient couplings with both vinyl and aryl stannanes, Furthermore, Pd/PR(NR′2)2 provides the first method for accomplishing Stille cross-couplings of simple alkyl iodides that bear β-hydrogen atoms.

引用

页码：5079 / 5082

页数：4

共 40 条

[1]

[Anonymous], ANGEW CHEM

[2]

Cardenas D. J., 1999, ANGEW CHEM, V111, P3201

[3] Advances in functional-group-tolerant metal-catalyzed alkyl-alkyl cross-coupling reactions [J].