Feasibility and efficacy of a new non-invasive surface cooling device in post-resuscitation intensive care medicine

被引:98
作者
Haugk, Moritz
Sterz, Fritz
Grassberger, Martin
Uray, Thomas
Kliegel, Andreas
Janata, Andreas
Richling, Nina
Herkner, Harald
Laggner, Anton N.
机构
[1] Med Univ Vienna, Dept Emergency Med, Vienna, Austria
[2] Med Univ Vienna, Dept Forens Med, Vienna, Austria
关键词
cardiac arrest; cardiopulmonary resuscitation (CPR); hypothermia; intensive care; post-resuscitation; period; temperature;
D O I
10.1016/j.resuscitation.2007.03.001
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Aim of the study: There is sufficient evidence that therapeutic hypothermia after non-traumatic cardiac arrest improves neurological outcome and reduces mortality. Many different invasive and non-invasive cooling devices are currently available. Our purpose was to show the efficacy, safety and feasibility using a non-invasive cooling device to control patient temperature within a range of 33-37 degrees C. Materials and methods: A convenience sample of patients who have been resuscitated successfully from cardiac arrest and were intended for mild hypothermia therapy according to the guidelines and inclusion criteria were studied in a prospective observational case series at an emergency department of a tertiary care university hospital. The Medivance Arctic Sun System provides a new, non-invasive approach to reach a target temperature of 33 degrees C quickly, to maintain the target temperature for 24 h, and then to actively re-warm at 0.4 degrees C/h to normothermia. Cooling was applied using the Arctic Sun in 27 patients. Data are presented as median and the interquartile range (25, 75%). Results: Median age was 58 (49.5, 70) years. Time from cooling start to target temperature was 137 (96, 168) min, cooling rate was 1.2 degrees C/h (0.8, 1.5), stability of target temperature during hypothermia maintenance phase was satisfactory at 33.0 degrees C (32.9, 33.1), and duration of re-warming was 428 (394, 452) min. Conclusion: Using the Arctic Sun System in post-resuscitation care medicine for cooling cardiac arrest survivors is feasible and has proven to be highly effective in lowering patients' temperature rapidly without inducing skin irritations.
引用
收藏
页码:76 / 81
页数:6
相关论文
共 9 条
  • [1] A prospective, multicenter pilot study to evaluate the feasibility and safety of using the CoolGard™ System and Icy™ catheter following cardiac arrest
    Al-Senani, FM
    Graffagnino, C
    Grotta, JC
    Saiki, R
    Wood, D
    Chung, W
    Palmer, G
    Collins, KA
    [J]. RESUSCITATION, 2004, 62 (02) : 143 - 150
  • [3] Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia
    Bernard, SA
    Gray, TW
    Buist, MD
    Jones, BM
    Silvester, W
    Gutteridge, G
    Smith, K
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (08) : 557 - 563
  • [4] *EUR RES COUNC, 2005, RESUSCITATION, V67, pS1, DOI DOI 10.1016/J.RESUSCITATION.2005.10.001
  • [5] Efficacy and safety of endovascular cooling after cardiac arrest -: Cohort study and Bayesian approach
    Holzer, Michael
    Muellner, Marcus
    Sterz, Fritz
    Robak, Oliver
    Kliegel, Andreas
    Losert, Heidrun
    Sodeck, Gottfried
    Uray, Thomas
    Zeiner, Andrea
    Laggner, Anton N.
    [J]. STROKE, 2006, 37 (07) : 1792 - 1797
  • [6] Cardiopulmonary cerebral resuscitation using emergency cardiopulmonary bypass, coronary reperfusion therapy and mild hypothermia in patients with cardiac arrest outside the hospital
    Nagao, K
    Hayashi, N
    Kanmatsuse, K
    Arima, K
    Ohtsuki, J
    Kikushima, K
    Watanabe, I
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2000, 36 (03) : 776 - 783
  • [7] Therapeutic hypothermia after cardiac arrest. An advisory statement by the Advanced Life Support Task Force of the International Liaison Committee on Resuscitation
    Nolan, JP
    Morley, PT
    Vanden Hoek, TL
    Hickey, RW
    [J]. RESUSCITATION, 2003, 57 (03) : 231 - 235
  • [8] Sterz Fritz, 2006, Acute Card Care, V8, P25, DOI 10.1080/14628840600621371
  • [9] Preliminary clinical outcome study of mild resuscitative hypothermia after out-of-hospital cardiopulmonary arrest
    Yanagawa, Y
    Ishihara, S
    Norio, H
    Takino, M
    Kawakami, M
    Takasu, A
    Okamoto, K
    Kaneko, N
    Terai, C
    Okada, Y
    [J]. RESUSCITATION, 1998, 39 (1-2) : 61 - 66