Synthetic studies on concanamycin A: Synthesis of the C5-C13 and C20-C28 segments

被引：19

作者：

Jyojima, T ^{[1
]}

Katohno, M ^{[1
]}

Miyamoto, N ^{[1
]}

Nakata, M ^{[1
]}

Matsumura, S ^{[1
]}

Toshima, K ^{[1
]}

机构：

[1] Keio Univ, Fac Sci & Technol, Dept Appl Chem, Kohoku Ku, Yokohama, Kanagawa 2238522, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 33期

关键词：

concanamycin A; macrolides; vacuolar H+-ATPase inhibitor; segment synthesis;

D O I：

10.1016/S0040-4039(98)01233-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enantioselective synthesis of the C5 similar to C13 (2) and C20 similar to C28 (3) segments, which are promising synthetic intermediates toward the total synthesis of the 18-membered macrolide antibiotic, concanamycin A (1), were described. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6003 / 6006

页数：4

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