Hit-and-run actions at dopamine receptors, part 1 mechanism of action of atypical antipsychotics

被引:21
作者
Stahl, SM
机构
[1] Univ Calif San Diego, Dept Psychiat, San Diego, CA 92103 USA
[2] Neurosci Educ Inst, Carlsbad, CA USA
关键词
D O I
10.4088/JCP.v62n0901
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Hypothetically, if an antipsychotic blocks a dopamine-2 receptor and then rapidly dissociates from it (i.e., "hit-and-run" action), it has atypical antipsychotic properties, namely reduction of psychosis without production of motor side effects.
引用
收藏
页码:670 / 671
页数:2
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