A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

被引:34
作者
Allin, SM
Northfield, CJ
Page, MI [1 ]
Slawin, AMZ
机构
[1] Loughborough Univ Technol, Dept Chem, Loughborough LE11 3TU, Leics, England
[2] Univ Huddersfield, Dept Chem & Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England
关键词
amino alcohols; aminals; stereocontrol; transition states; nitrogen heterocycles;
D O I
10.1016/S0040-4039(98)80041-5
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic gamma-lactam substrate as an N-acyliminium ion precursor. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:141 / 142
页数:2
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