TGFβ1 in liver fibrosis:: time to change paradigms?

被引：76

作者：

Bauer, M ^{[1
]}

Schuppan, D ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Dept Gastroenterol & Hepatol, Erlangen, Germany

来源：

FEBS LETTERS | 2001年 / 502卷 / 1-2期

关键词：

D O I：

10.1016/S0014-5793(01)02655-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：1 / 3

页数：3

共 22 条

[1]

BALLARDINI G, 1994, HEPATOLOGY, V19, P440

[2] Modulation of transforming growth factor β function in hepatocytes and hepatic stellate cells in rat liver injury [J].

Date, M ;

Matsuzaki, K ;

Matsushita, M ;

Tahashi, Y ;

Furukawa, F ;

Inoue, K .

GUT, 2000, 46 (05) :719-724

[3] Modulation of transforming growth factor β response and signaling during transdifferentiation of rat hepatic stellate cells to myofibroblasts [J].

Dooley, S ;

Delvoux, B ;

Lahme, B ;

Mangasser-Stephan, K ;

Gressner, AM .

HEPATOLOGY, 2000, 31 (05) :1094-1106

[4] Transforming growth factor β signal transduction in hepatic stellate cells via Smad2/3 phosphorylation, a pathway that is abrogated during in vitro progression to myofibroblasts -: TGFβ signal transduction during transdifferentiation of hepatic stellate cells [J].

Dooley, S ;

Delvoux, B ;

Streckert, M ;

Bonzel, L ;

Stopa, M ;

ten Dijke, P ;

Gressner, AM .

FEBS LETTERS, 2001, 502 (1-2) :4-10

[5]

FRIEDMAN SL, 1994, J BIOL CHEM, V269, P10551

[6] In vivo inhibition of rat stellate cell activation by soluble transforming growth factor β type II receptor:: A potential new therapy for hepatic fibrosis [J].

George, J ;

Roulot, D ;

Koteliansky, VE ;

Bissell, DM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (22) :12719-12724

[7]

Inagaki Y, 2001, J CELL PHYSIOL, V187, P117, DOI 10.1002/1097-4652(2001)9999:9999<00::AID-JCP1059>3.0.CO

[8]

2-S

[9] TGF-β1 in liver fibrosis:: an inducible transgenic mouse model to study liver fibrogenesis [J].

Kanzler, S ;

Lohse, AW ;

Keil, A ;

Henninger, J ;

Dienes, HP ;

Schirmacher, P ;

Rose-John, S ;

Zum Büschenfelde, KHM ;

Blessing, M .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1999, 276 (04) :G1059-G1068

[10] Localization of liver myofibroblasts and hepatic stellate cells in normal and diseased rat livers: distinct roles of (myo-)fibroblast subpopulations in hepatic tissue repair [J].

Knittel, T ;

Kobold, D ;

Piscaglia, F ;

Saile, B ;

Neubauer, K ;

Mehde, M ;

Timpl, R ;

Ramadori, G .

HISTOCHEMISTRY AND CELL BIOLOGY, 1999, 112 (05) :387-401

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