Classification of atrial fibrillation episodes from sparse electrocardiogram data

Background: Atrial fibrillation (AF) is the most common form of cardiac arrhythmia. This paper presents the application of the Classification and Regression Tree (CART) technique for detecting spontaneous termination or sustenance of AF with sparse data. Method: Electrocardiogram (ECG) recordings were obtained from the PhysioNet (AF Termination Challenge Database 2004) Web site. Signal analysis, feature extraction, and classification were made to distinguish among 3 AF episodes, namely, Nonterminating (N), Soon (<1 minute) to be terminating (S), and Terminating immediately (<1 second) (T). Results: A continuous wavelet transform whose basis functions match the EKG patterns was found to yield compact representation (similar to 2 orders of magnitude). This facilitates the development of efficient algorithms for beat detection, QRST subtraction, and multiple ECG quantifier extraction (eg, QRS width, QT interval). A compact feature set was extracted through principal component analysis of these quantifiers. Accuracies exceeding 90% for AF episode classification were achieved. Conclusions: A wavelet representation customized to the ECG signal pattern was found to yield 98% lower entropies compared with other representations that use standard library wavelets. The Classification and Regression Tree (CART) technique seems to distinguish the N vs T, and the S vs T classifications very accurately. (C) 2008 Elsevier Inc. All rights reserved.