Insecticidal anthranilic diamides: A new class of potent ryanodine receptor activators

被引：407

作者：

Lahm, GP ^{[1
]}

Selby, TP ^{[1
]}

Freudenberger, JH ^{[1
]}

Stevenson, TM ^{[1
]}

Myers, BJ ^{[1
]}

Seburyamo, G ^{[1
]}

Smith, BK ^{[1
]}

Flexner, L ^{[1
]}

Clark, CE ^{[1
]}

Cordova, D ^{[1
]}

机构：

[1] DuPont Crop Protect, Stine Haskell Res Ctr, Newark, DE 19711 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2005年 / 15卷 / 22期

关键词：

anthranilic; diamide; lepidoptera; ryanodine; receptor; insecticide;

D O I：

10.1016/j.bmcl.2005.08.034

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure-activity, and biological results are presented. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：4898 / 4906

页数：9

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