Insect-based BioFETs with improved signal characteristics

被引:23
作者
Schroth, P
Schöning, MJ
Kordos, P
Lüth, H
Schütz, S
Weissbecker, B
Hummel, HE
机构
[1] Forschungszentrum Julich, Inst Schicht & Ionentech, D-52425 Julich, Germany
[2] Univ Giessen, Inst Phytopathol & Angew Zool, Biol & Biotechn Pflanzenschutz, D-35390 Giessen, Germany
关键词
isolated-antenna BioFET; insect antennae; signal interfacing; intact chemoreceptor;
D O I
10.1016/S0956-5663(98)00131-6
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Insect-based BioFETs (biologically sensitive field-effect transistors) with improved signal characteristics have been developed. These BioFETs require a specifically adapted signal interfacing between a FET as signal transducer and an intact insect antenna as biocomponent. Therefore, different field-effect transistors have been fabricated in order to study the signal transfer at the bioelectronic interface. As relevant features of the BioFET, its current-voltage characteristics, the transconductance and the signal-to-noise ratio have been investigated as affected by the choice of gate insulator materials and gate dimensions (width-to-length ratio, thickness of the dielectric layers). The performance of the improved FET arrangement in the isolated-antenna BioFET was validated by employing dilution series of the plant odour component Z-3-hexen-1-ol. (C) 1999 Elsevier Science S.A. All rights reserved.
引用
收藏
页码:303 / 308
页数:6
相关论文
共 13 条
[1]  
BERGVELD P, 1988, COMPREHENSIVE ANAL C, V23, P18
[2]   INTACT CHEMORECEPTOR BIOSENSORS BASED ON HAWAIIAN AQUATIC SPECIES [J].
BUCH, RM ;
BARKER, TQ ;
RECHNITZ, GA .
ANALYTICA CHIMICA ACTA, 1991, 243 (02) :157-166
[3]   A NEURON-SILICON JUNCTION - A RETZIUS CELL OF THE LEECH ON AN INSULATED-GATE FIELD-EFFECT TRANSISTOR [J].
FROMHERZ, P ;
OFFENHAUSSER, A ;
VETTER, T ;
WEIS, J .
SCIENCE, 1991, 252 (5010) :1290-1293
[4]   NEURON TRANSISTOR - ELECTRICAL TRANSFER-FUNCTION MEASURED BY THE PATCH-CLAMP TECHNIQUE [J].
FROMHERZ, P ;
MULLER, CO ;
WEIS, R .
PHYSICAL REVIEW LETTERS, 1993, 71 (24) :4079-4082
[5]  
Kaissling K. E., 1995, EXPT CELL BIOL TASTE, P361
[6]   A BioFET on the basis of intact insect antennae [J].
Schoning, MJ ;
Schutz, S ;
Schroth, P ;
Weissbecker, B ;
Steffen, A ;
Kordos, P ;
Hummel, HE ;
Luth, H .
SENSORS AND ACTUATORS B-CHEMICAL, 1998, 47 (1-3) :235-238
[7]   Biosensor for volatiles released by damaged plants [J].
Schutz, S ;
Weissbecker, B ;
Hummel, HE .
BIOSENSORS & BIOELECTRONICS, 1996, 11 (04) :427-433
[8]   CAP-PCR Useful for Analyzing the Kin Relatedness of a Small Ant Species [J].
T. Murakami ;
Y. Ishibashi ;
S. Abe ;
M. C. Yoshida ;
S Higashi .
Naturwissenschaften, 1997, 84 (2) :86-88
[9]  
SCHUTZ S, 1998, UNPUB BIOSENSORS BIO
[10]   A UNIPOLAR FIELD-EFFECT TRANSISTOR [J].
SHOCKLEY, W .
PROCEEDINGS OF THE INSTITUTE OF RADIO ENGINEERS, 1952, 40 (11) :1365-1376