The diversity of endothelial cells: a challenge for therapeutic angiogenesis

被引:46
作者
Conway, EM [1 ]
Carmeliet, P [1 ]
机构
[1] Univ Leuven VIB, Gasthuisberg O&N, Ctr Transgene Technol & Gene Therapy, B-3000 Leuven, Belgium
关键词
D O I
10.1186/gb-2004-5-2-207
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Vascular endothelia comprise a diverse population of cells that specialize in response to genetic programs and environmental cues to take on distinct roles in different vessels, tissues, and organs, and in response to pathophysiological stresses. Characterization of endothelial-cell diversity will facilitate the development of novel, highly specific and safe therapies for many diseases.
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页数:5
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