FKBPs: at the crossroads of folding and transduction

被引:111
作者
Harrar, Y [1 ]
Bellini, C [1 ]
Faure, JD [1 ]
机构
[1] INRA, Biol Cellulaire Lab, F-78026 Versailles, France
关键词
D O I
10.1016/S1360-1385(01)02044-1
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
FK506-binding proteins (FKBPs) belong to the large family of peptidyl-prolyl cis-trans isomerases, which are known to be involved in many cellular processes, such as cell signalling, protein trafficking and transcription. FKBPs associate into protein complexes, although the involvement and precise role of their foldase activity remain to be elucidated. FKBPs represent a large gene family in plants that is involved in growth and development. Disruption of genes encoding FKBPs in plants and animals has underlined the importance of this family of proteins in the regulation of cell division and differentiation.
引用
收藏
页码:426 / 431
页数:6
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