Formal total synthesis of (±)-α- and β-cedrene by preparation of cedrone.: Construction of the tricyclic carbon skeleton by the use of a highly efficient intramolecular Khand annulation

被引：52

作者：

Kerr, WJ ^{[1
]}

McLaughlin, M ^{[1
]}

Morrison, AJ ^{[1
]}

Pauson, PL ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 19期

关键词：

D O I：

10.1021/ol016054a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The cedrene carbon skeleton was rapidly assembled from a simple monocyclic precursor by the strategic use of a high yielding intramolecular Khand cyclization reaction. Further synthetic manipulations provided a concise formal total synthesis of alpha- and beta -cedrene.

引用

页码：2945 / 2948

页数：4

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