NF1 tumor suppressor gene function: Narrowing the GAP

被引：457

作者：

Cichowski, K

Jacks, T

机构：

[1] Brigham & Womens Hosp, Dept Med, Div Genet, Boston, MA 02115 USA

[2] Harvard Univ, Sch Med, Boston, MA 02115 USA

[3] MIT, Ctr Canc Res, Dept Biol, Cambridge, MA 02139 USA

[4] MIT, Howard Hughes Med Inst, Cambridge, MA 02139 USA

来源：

CELL | 2001年 / 104卷 / 04期

关键词：

D O I：

10.1016/S0092-8674(01)00245-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：593 / 604

页数：12

共 87 条

[1] The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited fibroblasts [J].

Atit, RP ;

Crowe, MJ ;

Greenhalgh, DG ;

Wenstrup, RJ ;

Ratner, N .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1999, 112 (06) :835-842

[2]

BADER JL, 1986, ANN NY ACAD SCI, V486, P57

[3] THE NF1 LOCUS ENCODES A PROTEIN FUNCTIONALLY RELATED TO MAMMALIAN GAP AND YEAST IRA PROTEINS [J].

BALLESTER, R ;

MARCHUK, D ;

BOGUSKI, M ;

SAULINO, A ;

LETCHER, R ;

WIGLER, M ;

COLLINS, F .

CELL, 1990, 63 (04) :851-859

[4] ABERRANT REGULATION OF RAS PROTEINS IN MALIGNANT-TUMOR CELLS FROM TYPE-1 NEUROFIBROMATOSIS PATIENTS [J].

BASU, TN ;

GUTMANN, DH ;

FLETCHER, JA ;

GLOVER, TW ;

COLLINS, FS ;

DOWNWARD, J .

NATURE, 1992, 356 (6371) :713-715

[5]

BENNINGTON JL, 1978, MAJOR PROBLEMS PATHO

[6]

Berner JM, 1999, GENE CHROMOSOME CANC, V26, P151, DOI 10.1002/(SICI)1098-2264(199910)26:2<151::AID-GCC7>3.3.CO

[7]

2-1

[8] Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells [J].

Bollag, G ;

Clapp, DW ;

Shih, S ;

Adler, F ;

Zhang, YY ;

Thompson, P ;

Lange, BJ ;

Freedman, MH ;

McCormick, F ;

Jacks, T ;

Shannon, K .

NATURE GENETICS, 1996, 12 (02) :144-148

[9] DIFFERENTIAL REGULATION OF RASGAP AND NEUROFIBROMATOSIS GENE-PRODUCT ACTIVITIES [J].

BOLLAG, G ;

MCCORMICK, F .

NATURE, 1991, 351 (6327) :576-579

[10]

BOYER MJ, 1994, ONCOGENE, V9, P349

← 1 2 3 4 5 6 7 8 9 →