Polarized video imaging of skin.

被引:10
作者
Jacques, SL
Lee, K
机构
来源
LASERS IN SURGERY: ADVANCED CHARACTERIZATION, THERAPEUTICS, AND SYSTEMS VIII, PROCEEDINGS OF | 1998年 / 3245卷
关键词
optical diagnostics; polarized light; imaging; cancer; skin; dermatology;
D O I
10.1117/12.312307
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
A method for imaging the superficial epidermal and papillary dermal layers of the skin is needed when assessing many skin lesions. We have developed an imaging modality using a video camera whose mechanism of contrast is the reflectance of polarized light from superficial skin. By selecting only polarized light to create the image, one rejects the 95% of diffusely reflected Light from the deeper dermis. The specular reflectance (or glare) from the skin surface is also avoided in the setup. The resulting polarization picture maximally accents the details of the superficial layer of the skin and removes the effects of melanin pigmentation from the image. For example, freckles simply disappear and nevi lose their dark pigmentation to reveal the details of abnormal cellular growth. An initial clinical study demonstrated that the polarization camera could identify the margins of sclerosing basal cell carcinoma while the eye of the doctor underestimated the margin estimate. The camera identified an 11-mm-diameter lesion while the unaided eye identified a 6-mm-diameter lesion.
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页码:356 / 362
页数:7
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