Fibrin sealant sclerotherapy for treatment of lymphoceles following renal transplantation

被引:50
作者
Chin, AI
Ragavendra, N
Hilborne, L
Gritsch, HA
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Med Scientist Training Program, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiol, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Pathol & Lab Med, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, David Geffen Sch Med, Dept Urol, Los Angeles, CA 90095 USA
关键词
lymphocele; fibrin tissue adhesive; sclerotherapy; kidney transplantation;
D O I
10.1097/01.ju.0000074940.12565.80
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Fibrin sealant is used in various surgical fields for hemostasis and as an adhesive to approximate tissues. Its use was recently reported as a sclerosing agent for percutaneous treatment of lymphoceles following renal transplantation. We report on the use of fibrin glue sclerotherapy at this institution for the management of renal transplant related lymphoceles. Materials and Methods: We reviewed the records of 8 patients at a single institution with lymphoceles after renal transplantation treated with percutaneous fibrin glue sclerosis. Results: Treatment success was achieved in 6 patients (75%), with resolution of lymphoceles assessed with clinical and imaging findings. Four patients (50%) required 2 applications of fibrin sealant, with 2 (25%) subsequently requiring surgical management of the lymphoceles. Clinical followup averaged 27.7 months (range 4 to 44). Complications included lymphocele recurrence, clogging of drainage catheters and catheter dislodgement. Conclusions: The experience of 8 patients suggests that fibrin glue sclerotherapy may be considered a safe and effective method of treating symptomatic lymphoceles when simple percutaneous drainage has failed. The percutaneous approach does not require hospital admission and is less invasive than surgical treatment.
引用
收藏
页码:380 / 383
页数:4
相关论文
共 16 条
[1]  
Darras Frank S., 1997, Journal of Urology, V157, P429
[2]   LAPAROSCOPIC LYMPHOCELE DRAINAGE AFTER RENAL-TRANSPLANTATION [J].
FAHLENKAMP, D ;
RAATZ, D ;
SCHONBERGER, B ;
LOENING, SA .
JOURNAL OF UROLOGY, 1993, 150 (02) :316-318
[3]   FIBRIN GLUE - THE PERFECT OPERATIVE SEALANT [J].
GIBBLE, JW ;
NESS, PM .
TRANSFUSION, 1990, 30 (08) :741-747
[4]   POSTTRANSPLANT LYMPHOCELES - A CRITICAL-LOOK INTO THE RISK-FACTORS, PATHOPHYSIOLOGY AND MANAGEMENT [J].
KHAULI, RB ;
STOFF, JS ;
LOVEWELL, T ;
GHAVAMIAN, R ;
BAKER, S .
JOURNAL OF UROLOGY, 1993, 150 (01) :22-26
[5]   CT-guided percutaneous fibrin glue therapy of cerebrospinal fluid leaks in the spine after surgery [J].
Patel, MR ;
Caruso, PA ;
Yousuf, N ;
Rachlin, J .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2000, 175 (02) :443-446
[6]   FIBRIN GLUE FOR SEALING THE NEEDLE TRACK IN FINE-NEEDLE PERCUTANEOUS LUNG-BIOPSY USING A COAXIAL SYSTEM .2. CLINICAL-STUDY [J].
PETSAS, T ;
SIAMBLIS, D ;
GIANNAKENAS, C ;
TEPETES, K ;
DOUGENIS, D ;
SPIROPOULOS, K ;
FEZOULIDIS, I ;
DIMOPOULOS, I .
CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, 1995, 18 (06) :378-382
[7]   THE NATURAL-HISTORY OF AND THERAPY FOR PERIRENAL FLUID COLLECTIONS FOLLOWING RENAL-TRANSPLANTATION [J].
POLLAK, R ;
VEREMIS, SA ;
MADDUX, MS ;
MOZES, MF .
JOURNAL OF UROLOGY, 1988, 140 (04) :716-720
[8]   Fibrin sealant: Scientific rationale, production methods, properties, and current clinical use [J].
Radosevich, M ;
Goubran, HA ;
Burnouf, T .
VOX SANGUINIS, 1997, 72 (03) :133-143
[9]   Treatment of posttransplant lymphocele with povidone-iodine sclerosis: Long-term follow-up [J].
Rivera, M ;
Marcen, R ;
Burgos, J ;
Arranz, M ;
Rodriguez, R ;
Teruel, JL ;
Ortuno, J .
NEPHRON, 1996, 74 (02) :324-327
[10]   Percutaneous technique for management of persistent airspace with prolonged air leak using fibrin glue [J].
Samuels, LE ;
Shaw, PM ;
Blaum, LC .
CHEST, 1996, 109 (06) :1653-1655