Successful perioperative management of a patient with Parkinson's disease by enteral levodopa administration under propofol anesthesia

被引：26

作者：

Furuya, R ^{[1
]}

Hirai, A ^{[1
]}

Andoh, T ^{[1
]}

Kudoh, I ^{[1
]}

Okumura, F ^{[1
]}

机构：

[1] Yokohama City Univ, Sch Med, Dept Anesthesiol, Kanazawa Ku, Yokohama, Kanagawa 2360004, Japan

来源：

ANESTHESIOLOGY | 1998年 / 89卷 / 01期

关键词：

anesthetic technique; drug;

D O I：

10.1097/00000542-199807000-00035

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

PARKINSON'S disease (PD) is a relatively common neurologic disorder. Many drugs currently used for the treatment of PD map have significant interactions with anesthetic and cardiovascular drugs.(1) Even brief interruption of anti-PD drugs during surgery may result in exacerbation of Parkinson's symptoms.(2) However, safe and effective ways to administer anti-PD drugs during surgery are not widely known.(3) We used the enteral administration of levodopa (LD) in a patient with PD who had experienced exacerbation of PD during emergence from general anesthesia in two previous operations. This method of LD administration successfully prevented die exacerbation of the symptoms in this patient.

引用

页码：261 / 263

页数：3

共 14 条

[1]

COLEMAN RJ, 1990, Q J MED, V274, P1221

[2] PHARMACODYNAMIC MODELING OF ORAL LEVODOPA - CLINICAL-APPLICATION IN PARKINSONS-DISEASE [J].

CONTIN, M ;

RIVA, R ;

MARTINELLI, P ;

CORTELLI, P ;

ALBANI, F ;

BARUZZI, A .

NEUROLOGY, 1993, 43 (02) :367-371

[3]

DUTTON J, 1989, J NEUROSCI METH, V29, P271

[4] THE PHARMACOKINETICS OF INTRAVENOUS AND ORAL LEVODOPA IN PATIENTS WITH PARKINSONS-DISEASE WHO EXHIBIT ON-OFF FLUCTUATIONS [J].

HARDIE, RJ ;

MALCOLM, SL ;

LEES, AJ ;

STERN, GM ;

ALLEN, JG .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1986, 22 (04) :429-436

[5] ERRATIC GASTRIC-EMPTYING OF LEVODOPA MAY CAUSE RANDOM FLUCTUATIONS OF PARKINSONIAN MOBILITY [J].

KURLAN, R ;

ROTHFIELD, KP ;

WOODWARD, WR ;

NUTT, JG ;

MILLER, C ;

LICHTER, D ;

SHOULSON, I .

NEUROLOGY, 1988, 38 (03) :419-421

[6] DUODENAL AND GASTRIC DELIVERY OF LEVODOPA IN PARKINSONISM [J].

KURLAN, R ;

NUTT, JG ;

WOODWARD, WR ;

ROTHFIELD, K ;

LICHTER, D ;

MILLER, C ;

CARTER, JH ;

SHOULSON, I .

ANNALS OF NEUROLOGY, 1988, 23 (06) :589-595

[7] DUODENAL DELIVERY OF LEVODOPA FOR ON-OFF FLUCTUATIONS IN PARKINSONISM - PRELIMINARY-OBSERVATIONS [J].

KURLAN, R ;

RUBIN, AJ ;

MILLER, C ;

RIVERACALIMLIM, L ;

CLARKE, A ;

SHOULSON, I .

ANNALS OF NEUROLOGY, 1986, 20 (02) :262-265

[8] Surgical intervention and anesthetic management of the patient with Parkinson's disease [J].

Mason, LJ ;

Cojocaru, TT ;

Cole, DJ .

INTERNATIONAL ANESTHESIOLOGY CLINICS, 1996, 34 (04) :133-150

[9] EFFECTS OF L-DOPA ALONE AND IN COMBINATION WITH DOPA DECARBOXYLASE INHIBITORS ON ARTERIAL PRESSURE AND HEART RATE OF DOGS [J].

MINSKER, DH ;

SCRIABIN.A ;

STOKES, AI ;

STONE, CA ;

TORCHIAN.ML .

EXPERIENTIA, 1971, 27 (05) :529-&

[10]

REED AP, 1992, ANESTH ANALG, V75, P850

← 1 2 →