Chlorination of 20-oxopregnanes with the manganese dioxide chlorotrimethylsilane acetyl chloride system: A simple approach towards the construction of the corticosteroid side chain

被引：13

作者：

Borah, P ^{[1
]}

Ahmed, M ^{[1
]}

Chowdhury, P ^{[1
]}

机构：

[1] Reg Res Lab, Nat Prod Chem Div, Jorhat 785006, Assam, India

来源：

JOURNAL OF CHEMICAL RESEARCH-S | 1998年 / 05期

关键词：

D O I：

10.1039/a701350g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

C-21 chlorination of 20-oxosteroids using the system MnO2 (excess)-TMSCl or MnO2 (excess)-AcCl in acetic acid medium as well as an example of a Wagner-Meerwein rearrangement of 17 alpha-chloro-20-oxopregna-3 beta-yl acetate to 17 beta-methyl-18-nor-17 alpha-pregn-13-en-3 beta-yl acetate have been demonstrated.

引用

页码：236 / +

页数：2

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