Osteoarthritis year in review 2019: epidemiology and therapy

被引：462

作者：

Kloppenburg, M. ^{[1
,2
]}

Berenbaum, F. ^{[3
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Rheumatol, Leiden, Netherlands

[2] Leiden Univ, Med Ctr, Dept Clin Epidemiol, Leiden, Netherlands

[3] Sorbonne Univ, St Antoine Hosp, AP HP, INSERM,CRSA,Dept Rheumatol, Paris, France

来源：

OSTEOARTHRITIS AND CARTILAGE | 2020年 / 28卷 / 03期

基金：

欧盟地平线“2020”;

关键词：

Osteoarthritis; Epidemiology; Treatment; Clinical; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; KNEE OSTEOARTHRITIS; PAIN; HIP; ASSOCIATION; REPLACEMENT; MORTALITY; TRAMADOL; DISEASE; BURDEN;

D O I：

10.1016/j.joca.2020.01.002

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

Over the past year many studies and clinical trials have been published in the osteoarthritis (OA) field. This review is based on systematic literature review covering the period May 1st, 2018 to April 19th , 2019; the final selection of articles was subjective. Specifically those articles considered to be presenting novel insights and of potential importance for clinical practice, are discussed. Further evidence has emerged that OA is a serious disease with increasing impact worldwide. Our understanding of development of pain in OA has increased. Detailed studies investigating widely used pharmacological treatments have shown the benefits to be limited, whereas the risks seem higher than expected, suggesting further studies and reconsideration of currently used guidelines. Promising new pharmacological treatments have been developed and published, however subsequent studies are warranted. While waiting for new treatment modalities to appear joint replacement is an effective alternative; new data have become available on how long they might last. (C) 2020 The Authors. Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International.

引用

页码：242 / 248

页数：7

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