Hormonal control of the IGF system in the sea bream ovary

被引：22

作者：

Gioacchini, G

Cardinali, M

Maradonna, F

Funkenstein, B

Mosconi, G

Carnevali, O

机构：

[1] Univ Politecn Marche, Dipartimento Sci Mare, I-60131 Ancona, Italy

[2] Israel Oceanog & Limnol Res, Haifa, Israel

[3] Univ Camerino, Dipartimento Sci Morfol & Biochim Comparate, I-62032 Camerino, Italy

来源：

TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY | 2005年 / 1040卷

关键词：

estradiol; growth hormone; IGF binding proteins; IGF receptors;

D O I：

10.1196/annals.1327.051

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Numerous studies have described the presence of an intragonadal IGF system involved in regulation of gametogenesis in teleost fish. In the present study, the in vivo effects of estradiol-17 beta (E2) and growth hormone (GH) exposure on IGF-I, IGF-II, IGF1R, and IGFBP2 gene expression in sea bream ovary were monitored by RT-PCR during prereproductive and reproductive periods. The evidence demonstrates that both hormones investigated here affect the ovarian IGF system, showing that it is not only under GH control, but also can be regulated by sexual hormones; this hormonal modulation is related to reproductive phase.

引用

页码：320 / 322

页数：3

共 5 条

[1]

CARNEVALI O, 2004, IN PRESS MOL REP DEV

[2]

Gomez JM, 1999, J REPROD FERTIL, V115, P275, DOI 10.1530/jrf.0.1150275

[3]

INSULIN AND INSULIN-LIKE GROWTH-FACTOR-I AND GROWTH-FACTOR-II INDUCE FINAL MATURATION OF OOCYTES OF RED SEABREAM, PAGRUS-MAJOR, IN-VITRO [J].