Bioconjugation of biotinylated PAMAM dendrons to avidin

被引：27

作者：

Tao, Lei

Geng, Jin

Chen, Gaojian

Xu, Yingjian

Ladmiral, Vincent

Mantovani, Giuseppe

Haddleton, David. M. ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

[2] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

[3] Kyoto Univ, Div Organ Mat Chem, Kyoto 6110011, Japan

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 33期

关键词：

D O I：

10.1039/b709080c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The biotin-terminated PAMAM dendron has been synthesized and the asymmetric dendron used to modify the protein avidin via non-covalent bioconjugation.

引用

页码：3441 / 3443

页数：3

共 39 条

[1] New antibody purification procedure using a thermally responsive poly(N-isopropylacrylamide)-dextran derivative conjugate [J].

Anastase-Ravion, S ;

Ding, Z ;

Pellé, A ;

Hoffman, AS ;

Letourneur, D .

JOURNAL OF CHROMATOGRAPHY B, 2001, 761 (02) :247-254

[2] One-step synthesis of low polydispersity, biotinylated poly(N-isopropylacrylamide) by ATRP [J].

Bontempo, D ;

Li, RC ;

Ly, T ;

Brubaker, CE ;

Maynard, HD .

CHEMICAL COMMUNICATIONS, 2005, (37) :4702-4704

[3] Streptavidin as a macroinitiator for polymerization: In situ protein-polymer conjugate formation [J].

Bontempo, D ;

Maynard, HD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (18) :6508-6509

[4] Cysteine-reactive polymers synthesized by atom transfer radical polymerization for conjugation to proteins [J].

Bontempo, D ;

Heredia, KL ;

Fish, BA ;

Maynard, HD .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (47) :15372-15373

[5] Structure/function relationships of polyamidoamine/DNA dendrimers as gene delivery vehicles [J].

Braun, CS ;

Vetro, JA ;

Tomalia, DA ;

Koe, GS ;

Koe, JG ;

Middaugh, CR .

JOURNAL OF PHARMACEUTICAL SCIENCES, 2005, 94 (02) :423-436

[6] Site-specific polymer-streptavidin bioconjugate for pH-controlled binding and triggered release of biotin [J].

Bulmus, V ;

Ding, ZL ;

Long, CJ ;

Stayton, PS ;

Hoffman, AS .

BIOCONJUGATE CHEMISTRY, 2000, 11 (01) :78-83

[7] Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates [J].

Caliceti, P ;

Veronese, FM .

ADVANCED DRUG DELIVERY REVIEWS, 2003, 55 (10) :1261-1277

[8] Temperature control of biotin binding and release with a streptavidin-poly(N-isopropylacrylamide) site-specific conjugate [J].

Ding, ZL ;

Long, CJ ;

Hayashi, Y ;

Bulmus, EV ;

Hoffman, AS ;

Stayton, PS .

BIOCONJUGATE CHEMISTRY, 1999, 10 (03) :395-400

[9] Size-dependent control of the binding of biotinylated proteins to streptavidin using a polymer shield [J].

Ding, ZL ;

Fong, RB ;

Long, CJ ;

Stayton, PS ;

Hoffman, AS .

NATURE, 2001, 411 (6833) :59-62

[10] Synthesis and photoresponsive study of azobenzene centered polyamidoamine dendrimers [J].

Ghosh, S ;

Banthia, AK ;

Chen, Z .

TETRAHEDRON, 2005, 61 (11) :2889-2896

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