Hematopoietic stem cell transplantation for multiple sclerosis: finding equipoise

被引：6

作者：

Burt, RK

Kozak, T

机构：

[1] Northwestern Univ, Med Ctr, Chicago, IL 60611 USA

[2] Univ Hosp Kralovske Vinohrady, Dept Clin Haematol, Prague, Czech Republic

来源：

BONE MARROW TRANSPLANTATION | 2003年 / 32卷 / Suppl 1期

关键词：

multiple sclerosis; hematopoietic stem cell transplantation;

D O I：

10.1038/sj.bmt.1703942

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Hematopoietic stem cell transplantation of multiple sclerosis is rapidly expanding. Success for this approach requires an understanding of the pathophysiology of multiple sclerosis and design of trials that select patients with active inflammatory disease, low disability scores, and avoidance of conditioning agents that may damage neural stem cell compartments or further compromise already injured axons.

引用

页码：S45 / S48

页数：4

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