Differential antibiotic susceptibilities of starved Mycobacterium tuberculosis isolates

被引：116

作者：

Xie, ZF ^{[1
]}

Siddiqi, N ^{[1
]}

Rubin, EJ ^{[1
]}

机构：

[1] Harvard Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 11期

关键词：

D O I：

10.1128/AAC.49.11.4778-4780.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We compared the efficacies of 17 agents against rapidly growing and starved Mycobacterium tuberculosis H37Rv. Few compounds have significant activity at attainable concentrations. However, two phenothiazine compounds at similar concentrations were bactericidal for starved and growing cells. These drugs appear to target a process important in both replicating and nonreplicating bacteria.

引用

页码：4778 / 4780

页数：3

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