Catalyst selection for metal carbene transformations

被引：57

作者：

Timmons, DJ ^{[1
]}

Doyle, MP ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem, Tucson, AZ 85721 USA

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2001年 / 617卷 / 01期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

dirhodium(II) carboxamidates; metal carbene; asymmetric catalysis; diazo compound; cyclopropanation; insertion;

D O I：

10.1016/S0022-328X(00)00637-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Recent work has led to a greater understanding of the unique catalytic capabilities of chiral dirhodium(II) carboxamidates. High levels of product control, especially enantioselectivity, can be achieved with these catalysts in a wide variety of metal carbene transformations. Catalyst selection is the key to these applications that include addition, insertion, and ylide processes. Often two chiral dirhodium(II) carboxamidate catalysts applied to the same substrate provide exceptional selectivity, but for different products. (C) 2001 Published by Elsevier Science B.V.

引用

页码：98 / 104

页数：7

共 44 条

[1] Intramolecular regioselective insertion into unactivated prochiral carbon-hydrogen bonds with diazoacetates of primary alcohols catalyzed by chiral dirhodium(II) carboxamidates. Highly enantioselective total synthesis of natural lignan lactones [J].