Synthesis and characteristics of semi-interpenetrating polymer network hydrogels based on chitosan and poly(hydroxy ethyl methacrylate)

被引：30

作者：

Kim, SJ

Shin, SR

Shin, DI

Kim, IY ^{[1
]}

Kim, SI

机构：

[1] Hanyang Univ, Dept Biomed Engn, Seoul 133791, South Korea

[2] Asan Med Ctr, Dept Biomed Engn, Seoul, South Korea

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2005年 / 96卷 / 01期

关键词：

chitosan; poly(hydroxyethyl methacrylate); swelling behavior; pH sensitive;

D O I：

10.1002/app.21407

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Semi-interpenetrating polymer networks (semi-IPNs), composed of chitosan and poly(hydroxy ethyl methacrylate) hydrogels, were prepared and the effects of various pH, temperatures, and an electric-field on the swollen hydrogels were investigated. The swelling kinetics increased rapidly, reaching equilibrium within 60 min. Semi-IPN hydrogels exhibited relatively high swelling ratios, 150similar to350%. The swelling ratio increased when the pH of the buffer was below pH 7 as a result of the dissociation of ionic bonds. Semi-IPN hydrogels showed electroresponsivenes by shrinking when an electric field was applied. (C) 2005 Wiley Periodicals, Inc.

引用

页码：86 / 92

页数：7

共 29 条

[1] Diclofenac sodium releasing pH-sensitive monolithic devices [J].