Life's 24-hour clock: molecular control of circadian rhythms in animal cells

被引:81
作者
Young, MW
机构
[1] Rockefeller Univ, Genet Lab, New York, NY 10021 USA
[2] Rockefeller Univ, NSF, Ctr Biol Timing, New York, NY 10021 USA
关键词
D O I
10.1016/S0968-0004(00)01695-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Our sleep-wake cycles and many other similar to 24-hour rhythms of behavior and physiology persist in the absence of environmental cues. Genetic and biochemical studies have shown that such rhythms are controlled by internal molecular clocks. These are assembled from the cycling RNA and protein products of a small group of genes that are conserved throughout the animal kingdom.
引用
收藏
页码:601 / 606
页数:6
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