Use of a genetic algorithm to optimize TLC separation

被引:8
作者
Babic, S [1 ]
Horvat, AJM [1 ]
Kastelan-Macan, M [1 ]
机构
[1] Univ Zagreb, Fac Chem Engn & Technol, Analyt Chem Lab, HR-10000 Zagreb, Croatia
关键词
TLC; genetic algorithm; optimization; pesticides;
D O I
10.1556/JPC.18.2005.2.5
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A method for optimization of a TLC separation based on use of a genetic algorithm is described. The procedure was tested by optimization of the reversed-phase HPTLC separation of a mixture of six pesticides and satisfactory optimum results were obtained. The performance of the genetic algorithm was tested by measurement of the number of generations, the population size, the mutation probability, and the crossover probability. Three separation criteria (MRF, R* and R**) were examined as fitness functions. The genetic algorithm was compared with the simplex method.
引用
收藏
页码:112 / 117
页数:6
相关论文
共 8 条
[1]  
Babic S., 1998, KEM IND, V47, P275
[2]   A fast and precise genetic algorithm for a non-linear fitting problem [J].
Brunetti, A .
COMPUTER PHYSICS COMMUNICATIONS, 2000, 124 (2-3) :204-211
[3]  
CIMPOIU C, 2003, HDB THIN LAYER CHROM, P81
[4]   CRITERION FOR EVALUATION AND OPTIMIZATION IN THIN-LAYER CHROMATOGRAPHY [J].
DESPIEGELEER, BMJ ;
DEMOERLOOSE, PHM ;
SLEGERS, GAS .
ANALYTICAL CHEMISTRY, 1987, 59 (01) :62-64
[5]   Evolutionary computing [J].
Eiben, AE ;
Schoenauer, M .
INFORMATION PROCESSING LETTERS, 2002, 82 (01) :1-6
[6]   On the use of genetic algorithms for response surface modeling in high-performance liquid chromatography and their combination with the Microsoft Solver [J].
Nikitas, P ;
Pappa-Louisi, A ;
Papageorgiou, A ;
Zitrou, A .
JOURNAL OF CHROMATOGRAPHY A, 2002, 942 (1-2) :93-105
[7]   Planar chromatography at the turn of the century [J].
Poole, CF .
JOURNAL OF CHROMATOGRAPHY A, 1999, 856 (1-2) :399-427
[8]  
Wehrens R., 2000, Encyclopedia Anal. Chem., P9678