Isolation and characterization of a new Vesivirus from rabbits

被引：24

作者：

Martín-Alonso, JM

Skilling, DE

González-Molleda, A

del Barrio, G

Machín, A

Keefer, NK

Matson, DO

Iversen, PL

Smith, AW

Parra, F

机构：

[1] Univ Oviedo, Dept Bioquim & Biol Mol, Inst Univ Biotecnol Asturias, E-33006 Oviedo, Spain

[2] Oregon State Univ, Coll Vet Med, Lab Calicivirus Studies, Corvallis, OR 97331 USA

[3] Childrens Hosp Kings Daughters, Eastern Virginia Med Sch, Norfolk, VA 23507 USA

[4] AVI BioPharma, Corvallis, OR 97333 USA

来源：

VIROLOGY | 2005年 / 337卷 / 02期

关键词：

Caliciviridae; Vesivirus; RNA genome;

D O I：

10.1016/j.virol.2005.04.018

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

This report describes the isolation, cDNA cloning, complete genome nucleotide sequence, and partial characterization of a new cultivable calicivinis isolated from juvenile feeder European rabbits (Oryctolagus cuniculus) showing symptoms of diarrhea. Absence of neutralization by type-specific neutralizing antibodies for 40 caliciviruses and phylogenetic sequence comparisons of the open reading frame 1-encoded polyprotein with those of other caliciviruses demonstrate that this new calicivirus is a putative novel member of the Vesivirus genus which is closely related to the marine calicivirus subgroup. According to its putative classification, this new virus has been named rabbit vesivirus. (c) 2005 Elsevier Inc. All rights reserved.

引用

页码：373 / 383

页数：11

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