Yellow fever vector live-virus vaccines: West Nile virus vaccine development

被引：46

作者：

Arroyo, J ^{[1
]}

Miller, CA ^{[1
]}

Catalan, J ^{[1
]}

Monath, TP ^{[1
]}

机构：

[1] Acambis Inc, Cambridge, MA 02319 USA

来源：

TRENDS IN MOLECULAR MEDICINE | 2001年 / 7卷 / 08期

关键词：

D O I：

10.1016/S1471-4914(01)02048-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

By combining molecular-biological techniques with our increased understanding of the effect of gene sequence modification on viral function, yellow fever 17D, a positive-strand RNA virus vaccine, has been manipulated to induce a protective immune response against viruses of the same family (e.g. Japanese encephalitis and dengue viruses). Triggered by the emergence of West Nile virus infections in the New World afflicting humans, horses and birds, the success of this recombinant technology has prompted the rapid development of a live-virus attenuated candidate vaccine against West Nile virus.

引用

收藏

页码：350 / 354

页数：5

相关论文

共 37 条

[1]

Afzal MA, 2000, B WORLD HEALTH ORGAN, V78, P199

[2] Establishment and characterization of Japanese encephalitis virus-specific, human CD4+ T-cell clones:: Flavivirus cross-reactivity, protein recognition, and cytotoxic activity [J].

Aihara, H ;

Takasaki, T ;

Matsutani, T ;

Suzuki, R ;

Kurane, I .

JOURNAL OF VIROLOGY, 1998, 72 (10) :8032-8036

[3] Engineering the largest RNA virus genome as an infectious bacterial artificial chromosome [J].

Almazán, F ;

González, JM ;

Pénzes, Z ;

Izeta, A ;

Calvo, E ;

Plana-Durán, J ;

Enjuanes, L .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (10) :5516-5521

[4]

[Anonymous], 1999, JAPANESE ENCEPHALITI

[5] Molecular basis for attenuation of neurovirulence of a yellow fever virus/Japanese encephalitis virus chimera vaccine (ChimeriVax-JE) [J].

Arroyo, J ;

Guirakhoo, F ;

Fenner, S ;

Zhang, ZX ;

Monath, TP ;

Chambers, TJ .

JOURNAL OF VIROLOGY, 2001, 75 (02) :934-942

[6] ANTIGENIC RELATIONSHIPS BETWEEN FLAVIVIRUSES AS DETERMINED BY CROSS-NEUTRALIZATION TESTS WITH POLYCLONAL ANTISERA [J].

CALISHER, CH ;

KARABATSOS, N ;

DALRYMPLE, JM ;

SHOPE, RE ;

PORTERFIELD, JS ;

WESTAWAY, EG ;

BRANDT, WE .

JOURNAL OF GENERAL VIROLOGY, 1989, 70 :37-43

[7] RATIONAL USE OF MEASLES, MUMPS AND RUBELLA (MMR) VACCINE [J].

CARTER, H ;

CAMPBELL, H .

DRUGS, 1993, 45 (05) :677-683

[8] Yellow fever Japanese encephalitis chimeric viruses: Construction and biological properties [J].

Chambers, TJ ;

Nestorowicz, A ;

Mason, PW ;

Rice, CM .

JOURNAL OF VIROLOGY, 1999, 73 (04) :3095-3101

[9] West Nile virus recombinant DNA vaccine protects mouse and horse from virus challenge and expresses in vitro a noninfectious recombinant antigen that can be used in enzyme-linked immunosorbent assays [J].

Davis, BS ;

Chang, GJJ ;

Cropp, B ;

Roehrig, JT ;

Martin, DA ;

Mitchell, CJ ;

Bowen, R ;

Bunning, ML .

JOURNAL OF VIROLOGY, 2001, 75 (09) :4040-4047

[10] ESTABLISHMENT OF A GENOMIC BANK OF BOVINE HERPESVIRUS-1 USING A NOVEL POSITIVE SELECTION PLASMID VECTOR [J].

CHRISTENSEN, LS ;

BOYE, M .

JOURNAL OF VIROLOGICAL METHODS, 1992, 36 (03) :277-282

← 1 2 3 4 →