Sildenafil (Viagra) facilitates weaning of inhaled nitric oxide following placement of a biventricular-assist device

被引：34

作者：

Mychaskiw, G ^{[1
]}

Sachdev, V ^{[1
]}

Heath, BJ ^{[1
]}

机构：

[1] Univ Mississippi, Med Ctr, Dept Anesthesiol, Sch Med, Jackson, MS 39216 USA

来源：

JOURNAL OF CLINICAL ANESTHESIA | 2001年 / 13卷 / 03期

关键词：

pulmonary hypertension; therapies; phosphodiesterase; sildenafil;

D O I：

10.1016/S0952-8180(01)00252-5

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Sildenafil is a selective phosphodiesterase type 5 inhibitor used in the treatment of erectile dysfunction. We report the use of sildenafil to blunt the rebound pulmonary hypertension seen following withdrawal of inhaled nitric oxide (NO) and milrinone. The relatively long duration of sildenafil's action on pulmonary artery pressures and lack of systemic hemodynamic effect make it an attractive option to facilitate weaning of inhaled NO. (C) 2001 by Elsevier Science Inc.

引用

页码：218 / 220

页数：3

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