Rational Design and Enhanced Biocompatibility of a Dry Adhesive Medical Skin Patch

被引:299
作者
Kwak, Moon Kyu [1 ]
Jeong, Hoon-Eui [2 ]
Suh, Kahp Y. [1 ]
机构
[1] Seoul Natl Univ, Sch Mech & Aerosp Engn, Seoul 151742, South Korea
[2] Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
基金
新加坡国家研究基金会;
关键词
ALLERGIC CONTACT-DERMATITIS; SURFACES;
D O I
10.1002/adma.201101694
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new type of medical skin patch is developed that contains high-density, mushroom-like micropillars. Such dry-adhesive micropillars are highly biocompatible, have minimized side effects, and provide reasonable normal adhesion strength. To arrive at optimal conditions for the dry adhesive skin patch, the proper design of various structural and material parameters of micropillars is investigated.
引用
收藏
页码:3949 / +
页数:6
相关论文
共 32 条
[1]   From micro to nano contacts in biological attachment devices [J].
Arzt, E ;
Gorb, S ;
Spolenak, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (19) :10603-10606
[2]   Effective elastic modulus of isolated gecko setal arrays [J].
Autumn, K. ;
Majidi, C. ;
Groff, R. E. ;
Dittmore, A. ;
Fearing, R. .
JOURNAL OF EXPERIMENTAL BIOLOGY, 2006, 209 (18) :3558-3568
[3]   Evidence for van der Waals adhesion in gecko setae [J].
Autumn, K ;
Sitti, M ;
Liang, YCA ;
Peattie, AM ;
Hansen, WR ;
Sponberg, S ;
Kenny, TW ;
Fearing, R ;
Israelachvili, JN ;
Full, RJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (19) :12252-12256
[4]   Adhesive force of a single gecko foot-hair [J].
Autumn, K ;
Liang, YA ;
Hsieh, ST ;
Zesch, W ;
Chan, WP ;
Kenny, TW ;
Fearing, R ;
Full, RJ .
NATURE, 2000, 405 (6787) :681-+
[5]   Adhesion analysis of two-level hierarchical morphology in natural attachment systems for 'smart adhesion' [J].
Bhushan, Bharat ;
Peressadko, Andrei G. ;
Kim, Tae-Wan .
JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY, 2006, 20 (13) :1475-1491
[6]   Gecko-Inspired Surfaces: A Path to Strong and Reversible Dry Adhesives [J].
Boesel, Luciano F. ;
Greiner, Christian ;
Arzt, Eduard ;
del Campo, Aranzazu .
ADVANCED MATERIALS, 2010, 22 (19) :2125-2137
[7]   Patterned surfaces with pillars with controlled 3D tip geometry mimicking bioattachment devices [J].
del Campo, Aranzazu ;
Greiner, Christian ;
Alvarez, Irma ;
Arzt, Eduard .
ADVANCED MATERIALS, 2007, 19 (15) :1973-+
[8]   Super-hydrophobic surfaces: From natural to artificial [J].
Feng, L ;
Li, SH ;
Li, YS ;
Li, HJ ;
Zhang, LJ ;
Zhai, J ;
Song, YL ;
Liu, BQ ;
Jiang, L ;
Zhu, DB .
ADVANCED MATERIALS, 2002, 14 (24) :1857-1860
[9]   Microfabricated adhesive mimicking gecko foot-hair [J].
Geim, AK ;
Dubonos, SV ;
Grigorieva, IV ;
Novoselov, KS ;
Zhukov, AA ;
Shapoval, SY .
NATURE MATERIALS, 2003, 2 (07) :461-463
[10]   Biologically inspired crack trapping for enhanced adhesion [J].
Glassmaker, Nicholas J. ;
Jagota, Anand ;
Hui, Chung-Yuen ;
Noderer, William L. ;
Chaudhury, Manoj K. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (26) :10786-10791