Clostridium septicum infection and hemolytic uremic syndrome

Five cases of Clostridium septicum infection secondary to Escherichia coli O157-induced hemolytic uremic syndrome have been reported. We report on three cases (one of which is included in the above five) of dual CI. septicum and E. coli infection; all three patients were exposed to farm animals. A common zoonotic source for CI. septicum and E. coli O157 infections should be considered. Patients with hemolytic uremic syndrome should be treated aggressively and monitored closely for CI. septicum superinfection.