Julia-Colonna stereoselective epoxidation of some α,β-unsaturated enones possessing a stereogenic centre at the γ-position:: synthesis of a protected galactonic acid derivative

被引：18

作者：

Ray, PC ^{[1
]}

Roberts, SM ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Liverpool L69 7ZD, Merseyside, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2001年 / 02期

关键词：

D O I：

10.1039/b007100p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The oxidation of enones 6-8 using peroxide or percarbonate and polyleucines as catalysts gave the corresponding diastereomers 9-12 in high yield. The compound 9 was converted into the galactonic acid derivative 16 in five steps and in an overall yield of nearly 60%. Polyleucines are shown to be catalysts powerful enough to overturn the intrinsic stereocontrol in the chosen substrates.

引用

页码：149 / 153

页数：5

共 19 条

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