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Reduced ventral anterior cingulate and amygdala volumes in medication-naive females with major depressive disorder: A voxel-based morphometric magnetic resonance imaging study

被引：115
作者：
Tang, Yanqing
Wang, Fei
Xie, Guangrong
Liu, Jun
Li, Lehua
Su, Linyan
Liu, Ying
Hu, Xian
He, Zhong
Blumberg, Hilary P.
机构：
[1] S Cent Univ, Xiangya Hosp 2, Dept Psychiat, Changsha 410011, Peoples R China
[2] China Med Univ, Affiliated Hosp 1, Dept Psychiat, Shenyang 110001, Peoples R China
[3] Peking Univ, Natl Mental Hlth, Beijing 100083, Peoples R China
[4] Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06511 USA
[5] Dept Vet Affairs, West Haven, CT 06516 USA
来源：
PSYCHIATRY RESEARCH-NEUROIMAGING | 2007年 / 156卷 / 01期
基金：
中国国家自然科学基金;
关键词：
major depressive disorder; magnetic resonance imaging; voxel-based morphometry;
D O I：
10.1016/j.pscychresns.2007.03.005
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
High resolution magnetic resonance imaging and voxel-based morphometry were used to compare regional gray matter volumes between 14 medication-naive female participants with a first episode of major depressive disorder (MDD) and 13 female healthy comparison participants (HC). Volumes of bilateral ventral anterior cingulate cortex (vACC) and right amygdala were significantly smaller in the MDD group than in the HC group. These results suggest that volume reductions in vACC and amygdala in females with MDD are present at illness onset. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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收藏
页码：83 / 86
页数：4
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