The psychophysiology of anxiety disorder: Fear memory imagery

被引:215
作者
Cuthbert, BN [1 ]
Lang, PJ [1 ]
Strauss, C [1 ]
Drobes, D [1 ]
Patrick, CJ [1 ]
Bradley, MM [1 ]
机构
[1] Univ Florida, Hlth Sci Ctr, Ctr Study Emot & Attent, Gainesville, FL 32610 USA
关键词
anxiety; imagery; startle; depression; panic; PTSD;
D O I
10.1111/1469-8986.00043
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Psychophysiological response to fear memory imagery was assessed in specific phobia, social anxiety disorder, panic disorder with agoraphobia, post-traumatic stress disorder (PTSD), and healthy controls. Heart rate, skin conductance, and corrugator muscle were recorded as participants responded to tone cues signaling previously memorized descriptor sentences. Image contents included personal fears, social fears, fears of physical danger, and neutral (low arousal) scenes. Reactions to acoustic startle probes (eyeblink) were assessed during recall imagery and nonsignal periods. Participants were significantly more reactive (in physiology and report of affect) to fear than neutral cues. Panic and PTSD patients were, however, less physiologically responsive than specific phobics and the socially anxious. Panic and PTSD patients also reported the most anxiety and mood symptoms, and were most frequently comorbidly depressed. Overall, physiological reactivity to sentence memory cues was greatest in patients with focal fear of specific objects or events, and reduced in patients characterized by generalized, high negative affect.
引用
收藏
页码:407 / 422
页数:16
相关论文
共 88 条
[1]  
[Anonymous], 1987, DIAGNOSTIC STAT MANU, V4th
[2]  
[Anonymous], 2000, DIAGN STAT MAN MENT
[3]  
BARLOW DH, 1988, ANXIETY ITS DISORDER, P499
[4]   AN INVENTORY FOR MEASURING DEPRESSION [J].
BECK, AT ;
ERBAUGH, J ;
WARD, CH ;
MOCK, J ;
MENDELSOHN, M .
ARCHIVES OF GENERAL PSYCHIATRY, 1961, 4 (06) :561-&
[5]  
Beck AT., 1985, ANXIETY DISORDERS PH
[6]  
Benson H, 1975, RELAXATION RESPONSE
[7]   DEVELOPMENT, RELIABILITY, AND VALIDITY OF A DISSOCIATION SCALE [J].
BERNSTEIN, EM ;
PUTNAM, FW .
JOURNAL OF NERVOUS AND MENTAL DISEASE, 1986, 174 (12) :727-735
[8]   ATTACK AND DEFENSE IN RODENTS AS ETHOEXPERIMENTAL MODELS FOR THE STUDY OF EMOTION [J].
BLANCHARD, RJ ;
BLANCHARD, DC .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1989, 13 :S3-S14
[9]   INTERACTION OF EMOTION AND COGNITION IN WORD RECALL [J].
BOCK, M ;
KLINGER, E .
PSYCHOLOGICAL RESEARCH-PSYCHOLOGISCHE FORSCHUNG, 1986, 48 (02) :99-106
[10]   MODULATION OF SPINAL REFLEXES - AROUSAL, PLEASURE, ACTION [J].
BONNET, M ;
BRADLEY, MM ;
LANG, PJ ;
REQUIN, J .
PSYCHOPHYSIOLOGY, 1995, 32 (04) :367-372