Oxime bond formation for the covalent attachment of oligonucleotides on glass support

被引：38

作者：

Defrancq, E

Hoang, A

Vinet, F

Dumy, P

机构：

[1] Univ Grenoble 1, CNRS, UMR 5616, LEDSS, F-38041 Grenoble 9, France

[2] CEA, LETI, F-38054 Grenoble, France

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 16期

关键词：

D O I：

10.1016/S0960-894X(03)00537-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The chemical attachment of oligonucleotides on glass slides has been achieved using oxime bond formation. This method has been shown very efficient by comparison with the attachment of amino-oligonucleotides via reductive amination. (C) 2003 Elsevier Lt. All rights reserved.

引用

页码：2683 / 2686

页数：4