Discovery of herpesviruses in bats

被引:71
作者
Wibbelt, Gudrun
Kurth, Andreas
Yasmum, Nezlisah
Bannert, Michael
Nagel, Sabine
Nitsche, Andreas
Ehlers, Bernhard [1 ]
机构
[1] Robert Koch Inst, D-1000 Berlin, Germany
[2] Leibriz Inst Zoo & Wildlife Res Wildlife Dis Path, Berlin, Germany
关键词
D O I
10.1099/vir.0.83045-0
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Seven novel gammaherpesviruses (GHV) and one novel betaherpesvirus were discovered in seven different European bat species (order Chiroptera, family Vespertilionidae) with a pan-herpesvirus PCR assay, targeting the DNA polymerase (DPOL) gene. The sequences of six bat GHV were similarly related to members of the gammaherpesvirus genera Percavirus and Rhadinovirus. The seventh GHV was related to the porcine lymphotropic herpesvirus 1 (genus Macavirus). The betaherpesvirus appeared to be a distant relative of human cytomegalovirus. For three bat GHV a 3.6 kbp locus was amplified and sequenced, spanning part of the glycoprotein B gene and the majority of the DPOL gene. In phylogenetic analysis, the three bat GHV formed a separate clade with similar distance to the Percavirus and Rhadinovirus clades. These novel viruses are the first herpesviruses to be described in bats.
引用
收藏
页码:2651 / 2655
页数:5
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