A simple hydrophobicity-based score for profiling protein structures

被引：6

作者：

Alves, NA

Aleksenko, V

Hansmann, UHE

机构：

[1] Univ Sao Paulo, FFCLRP, Dept Fis & Matemat, BR-14040901 Ribeirao Preto, SP, Brazil

[2] Michigan Technol Univ, Dept Phys, Houghton, MI 49931 USA

来源：

JOURNAL OF PHYSICS-CONDENSED MATTER | 2005年 / 17卷 / 18期

关键词：

D O I：

10.1088/0953-8984/17/18/015

中图分类号：

O469 [凝聚态物理学];

学科分类号：

070205 ;

摘要：

We propose a simple measure that allows the profiling of protein configurations. It is based on calculation of a restricted radius of gyration evaluated only between the centroids of hydrophobic residues and measures the formation and compactness of the hydrophobic core. Some preliminary results for applications of the new score in generalized-ensemble simulations are presented.

引用

收藏

页码：S1595 / S1606

页数：12

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